Target Markets

Epidural Injections
The CompuFlo^® system’s pressure sensing technology provides an objective tool that consistently and accurately identifies the epidural space by correctly detecting the difference in pressure between the ligamentum flavum and the extraligamentary tissue. In studies utilizing the CompuFlo system, the epidural space has been correctly identified 100% of the time.  Knowing the precise location of a needle during an epidural injection procedure provides a measure of safety not presently available to doctors using conventional syringes, who identify the epidural space by relying on the subjective perception of loss of resistance to air or saline.  More specific, administering practitioners presently use his or her thumb as the only indicator of feedback to determine proper needle placement. 

Intra-Articular Injections
In the absence of curative procedures, arthritis patients are obliged to endure multiple painful injections each year over their lifetime. Often these injections are not efficacious, because the doctor using a manual syringe fails to locate the intra-articular space or fails to inject the appropriate volume of hyaluronic acid or other medicament into that space.  In an independent animal study, Milestone’s CompuFlo system has proven successful in administering medicaments into the intra-articular space using its computer-controlled pressure sensing capabilities.

Self-Administered Injections
There are a number of injectable drugs routinely self-administered in a home or office setting using spring loaded automatic injection devices by people who suffer from long term chronic conditions, such as auto-immune diseases like Multiple Sclerosis, Crohns Disease and Rheumatoid Arthritis, among others.   The CompuFlo system, using pressure sensing capabilities, can serve as a painless subcutaneous injection method for these self-administered drugs. A significant reduction in pain during delivery will have a positive impact on patient compliance with therapy adherence, which is a major consideration when physicians are determining which drugs to prescribe.

Neurosurgical Injections/Aspirations
The ability of the proven CompuFlo system technology to differentiate tissue type and precisely control infusion of drugs in-situ has a significant advantage to drug administration during surgical procedures.  Additionally, the CompuFlo system technology can also precisely regulate and control the aspiration of fluids, specific bodily tissues and/or foreign materials from fragile tissues, such as those that comprise the brain and the associated nerves of the central and peripheral nervous system.  The CompuFlo system technology is capable of identifying specific anatomic locations, thus enabling delicate micro-surgical procedures to be performed with greater precision and care resulting in reduced risk of bodily tissue damage.  It is these innovative technical attributes that Milestone believes will enable the CompuFlo system technology to dramatically improve clinical outcomes and ease of use for specific procedures performed during Neurosurgery.

Ophthalmic Injections
Milestone believes the development of a CompuFlo-based Ophthalmic Injection System to perform localized surgical procedures will enhance the efficiency and outcomes of routine ophthalmic surgery requiring local anesthesia, as well as precisely controlled pressure hydro-dissection during ophthalmic surgery.  Our patented technologies have been shown to effectively reduce or eliminate subjective pain, identify and differentiate specific tissue types, and deliver superior tactile and surgical control.  Consequently, the opportunity for Milestone to help advance the science and administration of Ophthalmic injections could prove to be pronounced and notably beneficial for the physician and the patient.

Dermal Filler/Cosmetic Surgery Injections
The CompuFlo system with DPS Dynamic Pressure Sensing^® technology provides an objective tool that can consistently and accurately maintains the optimal pressure for the placement of dermal fillers into soft facial tissue.  The controlled pressure can be regulated to minimize pain to patients.  Moreover, Milestone’s patented handpiece designs can prevent needle deflection, enabling the practitioner to more accurately and more consistently identify the specific location for placement of dermal fillers.  This increased tactile control, in combination with computer-controlled, pressure regulated and precise administration, creates the ideal condition that leads to superior outcomes and injection experiences for both the patient and the clinician.  With the use of a CompuFlo-Based Dermal Filler Injection System, risks can be significantly reduced and clinical outcomes can be materially improved.

Dental Injections
The CompuFlo system with DPS Dynamic Pressure Sensing technology are patented technologies that have been optimized and integrated as core technologies within the STA Single Tooth Anesthesia System^® unit, which is currently being sold into the worldwide dental market.